“The first historical record of psilocybin use dates back to Mesoamerica. Fungi were a prominent feature in Mixtec cultures, with over 5,000 different names of common edible mushrooms known across Mexican languages. A codex known as the “Yuta Tnoho” that belonged to the Mixtec culture in the 1500s BCE depicted religious and medicinal ritual ingestion of psilocybin-containing mushrooms. 

Psilocybin therapy is the use of psilocybin (the psychoactive ingredient in psilocybin mushrooms) in treating a range of mental health conditions, such as depression, anxiety, addictions, obsessive compulsive disorder (OCD), and psychosis. It is one of several forms of psychedelic therapy under study. Clinical trials are being conducted at universities and there is evidence confirming the use of psilocybin in the treatment of depression, post-traumatic stress disorder (PTSD) and end of life anxiety.”